[HTML][HTML] Exosomes: looking back three decades and into the future
CV Harding, JE Heuser, PD Stahl - The Journal of cell biology, 2013 - ncbi.nlm.nih.gov
CV Harding, JE Heuser, PD Stahl
The Journal of cell biology, 2013•ncbi.nlm.nih.govExosomes are extracellular membrane vesicles whose biogenesis by exocytosis of
multivesicular endosomes was discovered in 1983. Since their discovery 30 years ago, it
has become clear that exosomes contribute to many aspects of physiology and disease,
including intercellular communication. We discuss the initial experiments that led to the
discovery of exosomes and highlight some of the exciting current directions in the field.
multivesicular endosomes was discovered in 1983. Since their discovery 30 years ago, it
has become clear that exosomes contribute to many aspects of physiology and disease,
including intercellular communication. We discuss the initial experiments that led to the
discovery of exosomes and highlight some of the exciting current directions in the field.
Abstract
Exosomes are extracellular membrane vesicles whose biogenesis by exocytosis of multivesicular endosomes was discovered in 1983. Since their discovery 30 years ago, it has become clear that exosomes contribute to many aspects of physiology and disease, including intercellular communication. We discuss the initial experiments that led to the discovery of exosomes and highlight some of the exciting current directions in the field.
ncbi.nlm.nih.gov