Induction of tissue factor expression and release as microparticles in ECV304 cell line by Chlamydia pneumoniae infection
C Ettelaie, MEW Collier, NJ James, C Li - Atherosclerosis, 2007 - Elsevier
The association between Chlamydia pneumoniae (C. pneumoniae) infection and the onset
and progression of atherosclerosis has become apparent recently. Moreover, increased
expression of tissue factor (TF) as a result of C. pneumoniae infection has been previously
demonstrated. We have examined the expression of TF on the surface of endothelial cells
and the release of TF-containing cell-derived microparticles, over seven days. Additionally,
using cells expressing a procoagulantly active EGFP-TF hybrid protein, we examined the …
and progression of atherosclerosis has become apparent recently. Moreover, increased
expression of tissue factor (TF) as a result of C. pneumoniae infection has been previously
demonstrated. We have examined the expression of TF on the surface of endothelial cells
and the release of TF-containing cell-derived microparticles, over seven days. Additionally,
using cells expressing a procoagulantly active EGFP-TF hybrid protein, we examined the …