Relationship of Dendritic Cell Density, HMGB1 Expression, and Tumor-infiltrating Lymphocytes in Non–Small Cell Lung Carcinomas
D Aguilar-Cazares, M Meneses-Flores… - Applied …, 2014 - journals.lww.com
Lung cancer is the leading cause of cancer death worldwide and non–small cell lung
carcinoma (NSCLC) is the most common type of lung carcinomas. In adenocarcinomas, the
most frequent histologic type of NSCLC, dendritic cells (DCs) are localized in close contact
with tumor cells, and tumor-infiltrating lymphocytes (TILs) are observed in the peritumoral
zones. In NSCLC, no studies investigating the density of intratumoral DCs and their impact
on the density of TILs have been performed. In addition, the role of the alarmin high-mobility …
carcinoma (NSCLC) is the most common type of lung carcinomas. In adenocarcinomas, the
most frequent histologic type of NSCLC, dendritic cells (DCs) are localized in close contact
with tumor cells, and tumor-infiltrating lymphocytes (TILs) are observed in the peritumoral
zones. In NSCLC, no studies investigating the density of intratumoral DCs and their impact
on the density of TILs have been performed. In addition, the role of the alarmin high-mobility …
