Seckel syndrome is a rare autosomal recessive disorder, and its characteristic features
include prenatal and postnatal growth retardation, microcephaly, and “bird-like” face with
prominent, beak-like nose and micrognathia. Additional abnormalities were described in the
cardiovascular, hematopoietic, endocrine, and central nervous systems. We present the
magnetic resonance imaging findings of a neonate with Seckel syndrome accompanied by
semilobar holoprosencephaly and arthrogryposis. Major brain malformations may be …