The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease

T Tanaka, M Nangaku - Current opinion in nephrology and …, 2010 - journals.lww.com
T Tanaka, M Nangaku
Current opinion in nephrology and hypertension, 2010•journals.lww.com
The role of hypoxia, increased oxygen consumption, and hypox... : Current Opinion in
Nephrology and Hypertension The role of hypoxia, increased oxygen consumption, and
hypoxia-inducible factor-1 alpha in progression of chronic kidney disease : Current Opinion in
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Summary
Hypoxia, especially HIF-1, is a critical mediator in the pathogenesis of chronic kidney disease. Underlying molecular mechanisms, together with responsible HIF target genes, are currently under investigation.
Lippincott Williams & Wilkins
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