Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
G Bjelakovic, D Nikolova, LL Gluud, RG Simonetti… - Jama, 2007 - jamanetwork.com
Context Antioxidant supplements are used for prevention of several diseases. Objective To
assess the effect of antioxidant supplements on mortality in randomized primary and
secondary prevention trials. Data Sources and Trial Selection We searched electronic
databases and bibliographies published by October 2005. All randomized trials involving
adults comparing beta carotene, vitamin A, vitamin C (ascorbic acid), vitamin E, and
selenium either singly or combined vs placebo or vs no intervention were included in our …
assess the effect of antioxidant supplements on mortality in randomized primary and
secondary prevention trials. Data Sources and Trial Selection We searched electronic
databases and bibliographies published by October 2005. All randomized trials involving
adults comparing beta carotene, vitamin A, vitamin C (ascorbic acid), vitamin E, and
selenium either singly or combined vs placebo or vs no intervention were included in our …