International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and …

RT Jensen, JF Battey, ER Spindel, RV Benya - Pharmacological reviews, 2008 - Elsevier
The mammalian bombesin receptor family comprises three G protein-coupled heptahelical
receptors: the neuromedin B (NMB) receptor (BB 1), the gastrin-releasing peptide (GRP)
receptor (BB 2), and the orphan receptor bombesin receptor subtype 3 (BRS-3)(BB 3). Each
receptor is widely distributed, especially in the gastrointestinal (GI) tract and central nervous
system (CNS), and the receptors have a large range of effects in both normal physiology and
pathophysiological conditions. The mammalian bombesin peptides, GRP and NMB …