An introduction to Ebola: the virus and the disease

CJ Peters, JW Peters - The Journal of Infectious Diseases, 1999 - academic.oup.com
CJ Peters, JW Peters
The Journal of Infectious Diseases, 1999academic.oup.com
Filoviridae is the only known virus family about which we in many countries to prevent the
recurrence of disease introduced by imported monkeys [5], and tests were instituted to have
such profound ignorance. We do not even understand the maintenance strategies employed
in nature by the agents, and exclude Marburg virus from vaccine substrates [6]. Fortunately,
there have been only three detected recurrences of Marburg we know much less about the
resulting diseases, their pathogenesis, and detailed virology. The information gathered …
Filoviridae is the only known virus family about which we in many countries to prevent the recurrence of disease introduced by imported monkeys [5], and tests were instituted to have such profound ignorance. We do not even understand the maintenance strategies employed in nature by the agents, and exclude Marburg virus from vaccine substrates [6]. Fortunately, there have been only three detected recurrences of Marburg we know much less about the resulting diseases, their pathogenesis, and detailed virology. The information gathered during virus, all in humans traveling in rural Africa, and none of these has led to extensive transmission [7–9]. This brief history of control efforts directed toward recent epidemics has provided considerable fundamental information about filoviruses. Marburg virus presages the very similar course of events with Ebola virus. A number of colleagues, both in the laboratory and in the field, agreed to prepare reports reflecting recent research, thus permitting this supplement to the Journal of Infectious Dis-
Oxford University Press