Mechanisms involved in presynaptic depolarization of group I and rubrospinal fibers in cat spinal cord.

P Rudomin, I Engberg… - Journal of …, 1981 - journals.physiology.org
P Rudomin, I Engberg, I Jimenez
Journal of neurophysiology, 1981journals.physiology.org
5. These observations indicate that there is a substantial difference in the mechanisms of
presynaptic depolarization acting on group I afferent and descending fiber terminals in the
spinal cord. Group I afferent terminal arborizations both in the intermediate and motor nuclei
are the target of specific presynaptic depolarizing (presumably GABA-ergic) pathways. RS
(but not VS) fiber terminals may also be depolarized by stimulation of sensory nerves.
However, such PD does not appear to result from the activation of GABAergic pathways, but …
5. These observations indicate that there is a substantial difference in the mechanisms of presynaptic depolarization acting on group I afferent and descending fiber terminals in the spinal cord. Group I afferent terminal arborizations both in the intermediate and motor nuclei are the target of specific presynaptic depolarizing (presumably GABA-ergic) pathways. RS (but not VS) fiber terminals may also be depolarized by stimulation of sensory nerves. However, such PD does not appear to result from the activation of GABAergic pathways, but perhaps to extracellular accumulation of potassium.
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