Simplifying environmental cues in a Morris-type water maze improves place learning in old NMRI mice

Y Lamberty, AJ Gower - Behavioral and neural biology, 1991 - Elsevier
Old virgin female NMRI mice aged 17 months were compared with mice aged 3 months for
their spatial learning abilities in two versions of the Morris water maze. The first one was a
simplified version with a salient configuration of cues comparable to a black/white
discrimination and the second one was the classical version of the Morris test with many
distal cues surrounding the maze. In the simplified version, old mice presented a slower rate
of acquisition and a transient poorer retention compared to young mice. However, old mice …