Fatty liver (steatosis) is a common histological finding in human liver biopsies which is most
often attributed to the effects of alcohol excess, obesity, diabetes, or drugs. 1 The distribution
of lipid can be macrovesicular, with hepatocytes being distended by a single vacuole
displacing the nucleus or it can be microvesicular with numerous droplets surrounding a
centrally placed nucleus. Widespread microvesicular steatosis is characteristically an acute
condition in which impairment of fatty acid β-oxidation2 reflects a more general perturbation …