[PDF][PDF] Organogenesis and development of the liver

K Si-Tayeb, FP Lemaigre, SA Duncan - Developmental cell, 2010 - cell.com
K Si-Tayeb, FP Lemaigre, SA Duncan
Developmental cell, 2010cell.com
Embryonic development of the liver has been studied intensely, yielding insights that impact
diverse areas of developmental and cell biology. Understanding the fundamental
mechanisms that control hepatogenesis has also laid the basis for the rational differentiation
of stem cells into cells that display many hepatic functions. Here, we review the basic
molecular mechanisms that control the formation of the liver as an organ.
Summary
Embryonic development of the liver has been studied intensely, yielding insights that impact diverse areas of developmental and cell biology. Understanding the fundamental mechanisms that control hepatogenesis has also laid the basis for the rational differentiation of stem cells into cells that display many hepatic functions. Here, we review the basic molecular mechanisms that control the formation of the liver as an organ.
cell.com