Characterization of the severe asthma phenotype by the national heart, lung, and blood institute's severe asthma research program

WC Moore, ER Bleecker, D Curran-Everett… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Severe asthma causes the majority of asthma morbidity. Understanding
mechanisms that contribute to the development of severe disease is important. OBJECTIVE:
The goal of the Severe Asthma Research Program is to identify and characterize subjects
with severe asthma to understand pathophysiologic mechanisms in severe asthma.
METHODS: We performed a comprehensive phenotypic characterization (questionnaires,
atopy and pulmonary function testing, phlebotomy, exhaled nitric oxide) in subjects with …