Publisher Summary The visual cycle is a fundamental chemical transformation that
generates 11-cis-retinal from all-trans-retinal. The chromophore 11-cis-retinal recombines
with apoprotein opsin to form rhodopsin, the fight-sensitive receptor of the visual
transduction cascade. Several reactions are required for this transformation. 11-cis-Retinol
is produced enzymatically by an isomerase, which still has defied purification and molecular
characterization. To understand the production of 11-cis-retinal in retinal pigment epithelium …