Adrenergic mechanisms in myocardial infarction: cardiac and systemic catecholamine release
A Schömig - Journal of cardiovascular pharmacology, 1988 - journals.lww.com
A Schömig
Journal of cardiovascular pharmacology, 1988•journals.lww.comDuring myocardial ischemia high amounts of noradrenaline are released from the
sympathetic nerve terminals of the heart and accumulate in the extracellular space of the
ischemic area. This increase in local catecholamine concentrations within the still viable
myocardium may induce further deterioration of myocardial function during the ischemic
process, ie. acceleration of cell damage and induction of arrhythmias.
sympathetic nerve terminals of the heart and accumulate in the extracellular space of the
ischemic area. This increase in local catecholamine concentrations within the still viable
myocardium may induce further deterioration of myocardial function during the ischemic
process, ie. acceleration of cell damage and induction of arrhythmias.
Abstract
During myocardial ischemia high amounts of noradrenaline are released from the sympathetic nerve terminals of the heart and accumulate in the extracellular space of the ischemic area. This increase in local catecholamine concentrations within the still viable myocardium may induce further deterioration of myocardial function during the ischemic process, ie. acceleration of cell damage and induction of arrhythmias.
Lippincott Williams & Wilkins