microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients
R Hezova, O Slaby, P Faltejskova, Z Mikulkova… - Cellular …, 2010 - Elsevier
Regulatory T cells (Tregs) are critical regulators of autoimmune diseases, including type 1
diabetes mellitus. It is hypothesised that Tregs' function can be influenced by changes in the
expression of specific microRNAs (miRNAs). Thus, we performed miRNAs profiling in a
population of Tregs separated from peripheral blood of five type 1 diabetic patients and six
healthy donors. For more detailed molecular characterisation of Tregs, we additionally
compared miRNAs expression profiles of Tregs and conventional T cells. Tregs were …
diabetes mellitus. It is hypothesised that Tregs' function can be influenced by changes in the
expression of specific microRNAs (miRNAs). Thus, we performed miRNAs profiling in a
population of Tregs separated from peripheral blood of five type 1 diabetic patients and six
healthy donors. For more detailed molecular characterisation of Tregs, we additionally
compared miRNAs expression profiles of Tregs and conventional T cells. Tregs were …