OBJECTIVES: Multiple sclerosis (MS) is a chronic inflammatory response against
constituents of the central nervous system. It is known that regulatory T cells (Tregs) play a
key role in the autoimmune balance and their improper function may facilitate the expansion
of autoaggressive T cell clones. Recently, microRNAs (miRNAs) have been involved in
autoimmune disorders and their loss-of-function in immune cells was shown to facilitate
systemic autoimmune disorders. Here, we analyzed the miRNA expression profile in Tregs …