Early-life respiratory viral infections, atopic sensitization, and risk of subsequent development of persistent asthma
MMH Kusel, NH de Klerk, T Kebadze, V Vohma… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Severe lower respiratory infections (LRIs) and atopic sensitization have
been identified as independent risk factors for asthma. OBJECTIVE: The nature of potential
interactions between these risk factors was the subject of this study. METHODS: A
community-based cohort of 198 children at high atopic risk was followed from birth to 5
years. All episodes of acute respiratory illness in the first year were recorded and postnasal
aspirates were collected for viral identification. History of wheeze and asthma was collected …
been identified as independent risk factors for asthma. OBJECTIVE: The nature of potential
interactions between these risk factors was the subject of this study. METHODS: A
community-based cohort of 198 children at high atopic risk was followed from birth to 5
years. All episodes of acute respiratory illness in the first year were recorded and postnasal
aspirates were collected for viral identification. History of wheeze and asthma was collected …