Vertebrate photoreceptor cell development and disease
EM Morrow, T Furukawa, CL Cepko - Trends in cell biology, 1998 - cell.com
EM Morrow, T Furukawa, CL Cepko
Trends in cell biology, 1998•cell.comPhotoreceptors provide an excellent model for studies of vertebrate neuronal differentiation,
and many human diseases resulting in blindness primarily affect photoreceptors. There is
therefore great interest in studying the cellular and molecular mechanisms of photoreceptor
development. This article discusses our current understanding of this process, including the
recent discovery of the homeodomain transcription factor Crx and its potential role in
diseases affecting human vision.
and many human diseases resulting in blindness primarily affect photoreceptors. There is
therefore great interest in studying the cellular and molecular mechanisms of photoreceptor
development. This article discusses our current understanding of this process, including the
recent discovery of the homeodomain transcription factor Crx and its potential role in
diseases affecting human vision.
Abstract
Photoreceptors provide an excellent model for studies of vertebrate neuronal differentiation, and many human diseases resulting in blindness primarily affect photoreceptors. There is therefore great interest in studying the cellular and molecular mechanisms of photoreceptor development. This article discusses our current understanding of this process, including the recent discovery of the homeodomain transcription factor Crx and its potential role in diseases affecting human vision.
cell.com