Gastrointestinal dysfunction in Parkinson's disease

RF Pfeiffer - Parkinsonism & related disorders, 2011 - Elsevier
Parkinsonism & related disorders, 2011Elsevier
In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting
of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all
levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess,
dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction
all may occur. The pathophysiologic basis for this dysfunction entails both central and
enteric nervous system involvement.
In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson’s disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiologic basis for this dysfunction entails both central and enteric nervous system involvement.
Elsevier