[HTML][HTML] Nonalcoholic fatty liver disease is associated with hepatic and skeletal muscle insulin resistance in overweight adolescents
S Deivanayagam, BS Mohammed, BE Vitola… - The American journal of …, 2008 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) and insulin resistance are common in
overweight adolescents. Objective The purpose of this study was to determine the relation
between NAFLD and insulin sensitivity in liver and skeletal muscle by studying overweight
adolescents with a normal or high intrahepatic triglyceride (IHTG) content, who were
matched for age, sex, body mass index (BMI; in kg/m 2), and Tanner stage. Design Stable-
isotope-labeled tracer infusion and the hyperinsulinemic-euglycemic clamp procedure were …
overweight adolescents. Objective The purpose of this study was to determine the relation
between NAFLD and insulin sensitivity in liver and skeletal muscle by studying overweight
adolescents with a normal or high intrahepatic triglyceride (IHTG) content, who were
matched for age, sex, body mass index (BMI; in kg/m 2), and Tanner stage. Design Stable-
isotope-labeled tracer infusion and the hyperinsulinemic-euglycemic clamp procedure were …