Evaluation of cardiovascular and ECG parameters in the normal, freely moving Göttingen Minipig

M Stubhan, M Markert, K Mayer, T Trautmann… - … of Pharmacological and …, 2008 - Elsevier
INTRODUCTION: The objective of this study was to evaluate the normal cardiovascular and
ECG parameters in freely moving minipigs and to use these data as the basis of
pharmacological drug safety evaluation. METHODS: 7 Göttingen Minipigs were equipped
with radiotelemetry transmitters (ITS). Aortic pressure (AP), left ventricular pressure (LVP),
lead II of the ECG and body temperature were continuously monitored. Notocord HEM 4.2
software was used for data acquisition. Power calculations for the various parameters were …