[HTML][HTML] Col1a1 promoter-targeted expression of p20 CCAAT enhancer-binding protein β (C/EBPβ), a truncated C/EBPβ isoform, causes osteopenia in transgenic …
JR Harrison, YF Huang, KA Wilson, PL Kelly… - Journal of Biological …, 2005 - ASBMB
CCAAT enhancer-binding protein (C/EBP) transcription factors regulate adipocyte
differentiation, and recent evidence suggests that osteoblasts and adipocytes share a
common pluripotent progenitor in bone marrow. However, little is known about the role of
C/EBP transcription factors in the control of osteoblast differentiation or function. In this study,
the function of C/EBP transcription factors was disrupted in osteoblast lineage cells by
overexpressing a naturally occurring dominant negative C/EBP isoform. Expression of …
differentiation, and recent evidence suggests that osteoblasts and adipocytes share a
common pluripotent progenitor in bone marrow. However, little is known about the role of
C/EBP transcription factors in the control of osteoblast differentiation or function. In this study,
the function of C/EBP transcription factors was disrupted in osteoblast lineage cells by
overexpressing a naturally occurring dominant negative C/EBP isoform. Expression of …