Residual dipolar coupling of the Cr/PCr methyl resonance in resting human medial gastrocnemius muscle

CC Hanstock, RB Thompson, ME Trump… - … in Medicine: An …, 1999 - Wiley Online Library
CC Hanstock, RB Thompson, ME Trump, D Gheorghiu, PW Hochachka, PS Allen
Magnetic Resonance in Medicine: An Official Journal of the …, 1999Wiley Online Library
This paper presents a detailed analysis of the TE dependence of the creatine methyl proton
signal at 3.02 ppm, resulting from a symmetric PRESS sequence applied to the resting
human gastrocnemius muscle. The analysis shows that a two‐component decay of the
central peak of the dipolar‐coupled‐methyl triplet should be interpreted as the superposition
of a rapid (≈ 34 msec) dipolar dephasing and a less rapid (≈ 162 msec) transverse
relaxation. These data do not support a two‐pool hypothesis for TE dependence of this …
Abstract
This paper presents a detailed analysis of the TE dependence of the creatine methyl proton signal at 3.02 ppm, resulting from a symmetric PRESS sequence applied to the resting human gastrocnemius muscle. The analysis shows that a two‐component decay of the central peak of the dipolar‐coupled‐methyl triplet should be interpreted as the superposition of a rapid (≈34 msec) dipolar dephasing and a less rapid (≈162 msec) transverse relaxation. These data do not support a two‐pool hypothesis for TE dependence of this signal. Magn Reson Med 42:421–424, 1999. © 1999 Wiley‐Liss, Inc.
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