Clinical evaluation of chemotherapeutic agents in the treatment of primary liver cancer

T Ohya, S Kikuchi - Gan to Kagaku ryoho. Cancer & Chemotherapy, 1982 - europepmc.org
T Ohya, S Kikuchi
Gan to Kagaku ryoho. Cancer & Chemotherapy, 1982europepmc.org
For the comparison of effect of FT-207 alone and FT-207+ MMC combination chemotherapy
on primary hepatocellular carcinoma, 41 patients were entered into the trial. Thirty-two cases
whose data were evaluable were studied by Koyama's classification. There was only one
effective case (6.6%) in single agent group (15 cases) and 5 cases (29.4%) were effective in
combination chemotherapy (17 cases). MMC combination chemotherapy was more effective
on regression in size of hepatomegaly than FT-207 alone. By osaka group classification, 5 …
For the comparison of effect of FT-207 alone and FT-207+ MMC combination chemotherapy on primary hepatocellular carcinoma, 41 patients were entered into the trial. Thirty-two cases whose data were evaluable were studied by Koyama's classification. There was only one effective case (6.6%) in single agent group (15 cases) and 5 cases (29.4%) were effective in combination chemotherapy (17 cases). MMC combination chemotherapy was more effective on regression in size of hepatomegaly than FT-207 alone. By osaka group classification, 5 cases (33.3%) in single agent group (15 cases) were effective, and 10 cases in combination group (17 cases)(58.8%) were effective. The slight side effect often necessitated upon cessation of the treatment in 31 cases but the disappeared on cessation or by decrease of dose.
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