Nemaline myopathy: comparative muscle histochemistry in the severe neonatal, moderate congenital, and adult-onset forms

C Shimomura, I Nonaka - Pediatric Neurology, 1989 - Elsevier
A histochemical study of biopsied muscle specimens from patients with the 3 forms of
nemaline myopathy (ie, severe neonatal, moderate congenital, and adult-onset), classified
on the basis of clinical symptoms, was conducted. A close relationship could not be found
between the number of rods and the severity of weakness in any form. Type 1 fiber atrophy
and predominance or type 2B fiber deficiency was the usual finding in all forms. In the
moderate congenital form, type 1 fiber atrophy and predominance became more apparent in …