[HTML][HTML] Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth
T Kinnunen, M Kaksonen, J Saarinen… - Journal of Biological …, 1998 - ASBMB
N-syndecan (syndecan-3) was previously isolated as a cell surface receptor for heparin-
binding growth-associated molecule (HB-GAM) and suggested to mediate the neurite
growth-promoting signal from cell matrix-bound HB-GAM to the cytoskeleton of neurites.
However, it is unclear whether N-syndecan would possess independent signaling capacity
in neurite growth or in related cell differentiation phenomena. In the present study, we have
transfected N18 neuroblastoma cells with a rat N-syndecan cDNA and show that N …
binding growth-associated molecule (HB-GAM) and suggested to mediate the neurite
growth-promoting signal from cell matrix-bound HB-GAM to the cytoskeleton of neurites.
However, it is unclear whether N-syndecan would possess independent signaling capacity
in neurite growth or in related cell differentiation phenomena. In the present study, we have
transfected N18 neuroblastoma cells with a rat N-syndecan cDNA and show that N …