Many clinically important enteric pathogens initiate disease by invading and passing
through the intestinal epithelium, a process accompanied by increased epithelial expression
of proinflammatory cytokines. To further define the role intestinal epithelial cells play in
initiating and modulating the host response to infection with invasive bacteria, hybrid
selection on high density cDNA arrays was used to characterize the mRNA expression
profile of∼ 4,300 genes in human intestinal epithelial cells after infection with the prototypic …