Immune modulating peptides for the treatment and suppression of multiple sclerosis

AH Badawi, TJ Siahaan - Clinical immunology, 2012 - Elsevier
Multiple sclerosis (MS) is a neurodegenerative disease in which the immune system
recognizes proteins of the myelin sheath as antigenic, thus initiating an inflammatory
reaction in the central nervous system. This leads to demyelination of the axons, breakdown
of the blood–brain barrier, and lesion formation. Current therapies for the treatment of MS
are generally non-specific and weaken the global immune system, thus making the
individual susceptible to opportunistic infections. Antigenic peptides and their derivatives are …