Integrating global gene expression analysis and genetics

CR Farber, AJ Lusis - Advances in genetics, 2008 - Elsevier
The transcriptome is defined as the collection of all RNAs produced in a cell or tissue at a
defined time in development and is one of many stages that make up a biological system. It
is also one of the most important; providing the critical link in the flow of information between
genes and disease. Therefore, identifying gene expression changes that are reacting to or
causing disease promises to significantly enhance our understanding of common disorders.
However, only recently has the technology, in the form of DNA microarrays, been in place to …