Virulence in Cryptococcus species

H Ma, RC May - Advances in applied microbiology, 2009 - Elsevier
Cryptococcus neoformans and Cryptococcus gattii are the cause of life-threatening
meningoencephalitis in immunocompromised and immunocompetent individuals
respectively. The increasing incidence of cryptococcal infection as a result of the AIDS
epidemic, the recent emergence of a hypervirulent cryptococcal strain in Canada and the
fact that mortality from cryptococcal disease remains high have stimulated intensive
research into this organism. Here we outline recent advances in our understanding of C …