Clinical and brain imaging heterogeneity of severe microcephaly
L Basel-Vanagaite, WB Dobyns - Pediatric neurology, 2010 - Elsevier
Microcephaly may be present at birth or develop postnatally. Classification according to the
genetic cause cannot always predict the severity of the clinical course. The aim of this
research was to group a large cohort of patients with primary microcephaly into more
discrete subtypes, to optimize assessment of the patients based on their clinical and brain
imaging findings. Medical records and brain images were reviewed for 4442 patients with
brain malformations diagnosed and treated over 24 years and identified 247 patients …
genetic cause cannot always predict the severity of the clinical course. The aim of this
research was to group a large cohort of patients with primary microcephaly into more
discrete subtypes, to optimize assessment of the patients based on their clinical and brain
imaging findings. Medical records and brain images were reviewed for 4442 patients with
brain malformations diagnosed and treated over 24 years and identified 247 patients …