[HTML][HTML] First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours
British journal of cancer, 2006•nature.com
The lymphatic system is the primary pathway of metastasis for most human cancers. Recent
research efforts in studying lymphangiogenesis have suggested the existence of a
relationship between lymphatic vessel density and patient survival. However, current
methodology of lymphangiogenesis quantification is still characterised by high intra-and
interobserver variability. For the amount of lymphatic vessels in a tumour to be a clinically
useful parameter, a reliable quantification technique needs to be developed. With this …
research efforts in studying lymphangiogenesis have suggested the existence of a
relationship between lymphatic vessel density and patient survival. However, current
methodology of lymphangiogenesis quantification is still characterised by high intra-and
interobserver variability. For the amount of lymphatic vessels in a tumour to be a clinically
useful parameter, a reliable quantification technique needs to be developed. With this …
Abstract
The lymphatic system is the primary pathway of metastasis for most human cancers. Recent research efforts in studying lymphangiogenesis have suggested the existence of a relationship between lymphatic vessel density and patient survival. However, current methodology of lymphangiogenesis quantification is still characterised by high intra-and interobserver variability. For the amount of lymphatic vessels in a tumour to be a clinically useful parameter, a reliable quantification technique needs to be developed. With this consensus report, we therefore would like to initiate discussion on the standardisation of the immunohistochemical method for lymphangiogenesis assessment.
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