Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells

YL Yamaguchi, SS Tanaka, M Kasa, K Yasuda… - Gene expression …, 2006 - Elsevier
The low density lipoprotein receptor-related protein 4 gene (Lrp4) was identified by
subtractive screening of cDNAs of the migratory primordial germ cells (PGCs) of E8. 5–9.5
embryo and E3. 5 blastocysts. Lrp4 is expressed in PGCs in the hindgut and the dorsal
mesentery of E9. 5 embryos, and in germ cells in the genital ridges of male and female E10.
5–13.5 embryos. Lrp4 is also expressed in spermatogonia of the neonatal and adult testes
and in the immature oocytes and follicular cells of the adult ovary. The absence of Lrp4 …