Platelet preservation: effect of storage temperature on maintenance of platelet viability—deleterious effect of refrigerated storage
S Murphy, FH Gardner - New England Journal of Medicine, 1969 - Mass Medical Soc
S Murphy, FH Gardner
New England Journal of Medicine, 1969•Mass Medical SocStandard refrigerated storage (at 4° C) resulted in a marked shortening of the life-span of
platelets labeled with 51Cr and reinfused into the original donor. Storage at ambient, room
temperature (22° C) preserved a normal platelet life-span. Platelets stored at this higher
temperature should be adequate for transfusion purposes for as long as 96 hours. The use
of cold temperatures should be abandoned in the preparation and storage of platelets for
transfusion purposes.
platelets labeled with 51Cr and reinfused into the original donor. Storage at ambient, room
temperature (22° C) preserved a normal platelet life-span. Platelets stored at this higher
temperature should be adequate for transfusion purposes for as long as 96 hours. The use
of cold temperatures should be abandoned in the preparation and storage of platelets for
transfusion purposes.
Abstract
Standard refrigerated storage (at 4°C) resulted in a marked shortening of the life-span of platelets labeled with 51Cr and reinfused into the original donor. Storage at ambient, room temperature (22°C) preserved a normal platelet life-span. Platelets stored at this higher temperature should be adequate for transfusion purposes for as long as 96 hours. The use of cold temperatures should be abandoned in the preparation and storage of platelets for transfusion purposes.
The New England Journal Of Medicine