Yield enhancement of a double-quantum filter sequence designed for the edited detection of GABA
AH Wilman, PS Allen - Journal of Magnetic Resonance, Series B, 1995 - Elsevier
To overcome limitations in the signal to noise ratio (S/N) of previously proposed multiple-
quantum filters (MQFs), designed for editing the GABA A2multiplet from the creatine (Cr)
singlet in proton spectroscopy of brain, a new double-quantum filter is proposed which
significantly enhancesS/N (thereby making it comparable with the spin-echo difference
editing technique) while maintaining the superior Cr suppression and zero vulnerability to
subtraction errors of previously proposed MQFs. TheS/Nenhancement results primarily from …
quantum filters (MQFs), designed for editing the GABA A2multiplet from the creatine (Cr)
singlet in proton spectroscopy of brain, a new double-quantum filter is proposed which
significantly enhancesS/N (thereby making it comparable with the spin-echo difference
editing technique) while maintaining the superior Cr suppression and zero vulnerability to
subtraction errors of previously proposed MQFs. TheS/Nenhancement results primarily from …