Synthesis and lymphatic transport of intestinal apolipoprotein A-IV in response to graded doses of triglyceride.

TJ Kalogeris, K Fukagawa, P Tso - Journal of lipid research, 1994 - ASBMB
Factors regulating the intestinal synthesis and secretion of apoA-IV are incompletely
understood. Although it is known that apoA-IV is stimulated by dietary lipid, it is not known
whether graded doses of triglyceride elicit graded responses in apoA-IV synthesis and
secretion. We used the chronic intestinal lymph-fistula rat to examine the effect of graded
levels of intestinal triglyceride transport on secretion of apoA-IV into lymph and synthesis of
apoA-IV in various regions of intestine. Rats were implanted with chronic duodenal and …