Relationship of body temperature stability to mortality in aging mice
MA Reynolds, DK Ingram, M Talan - Mechanisms of ageing and …, 1985 - Elsevier
An age-related decline in the capacity for thermoregulation among homeothermic animals
has been observed frequently under conditions of extreme ambient temperatures. We
investigated the temporal stability of the internal body temperature of 69 C57BL/6J mice from
25 months of age until death in a controlled, neutral thermal environment. Estimates of
temporal variability were calculated over consecutive 1-month intervals using (colonic) body
temperature data collected weekly. The results of this longitudinal analysis indicated that the …
has been observed frequently under conditions of extreme ambient temperatures. We
investigated the temporal stability of the internal body temperature of 69 C57BL/6J mice from
25 months of age until death in a controlled, neutral thermal environment. Estimates of
temporal variability were calculated over consecutive 1-month intervals using (colonic) body
temperature data collected weekly. The results of this longitudinal analysis indicated that the …