The effect of fasting and refeeding on thyroid follicule structure and thyroid hormone levels in young and old rats

Z Kmieć, G Kotlarz, B Śmiechowska… - Archives of gerontology …, 1998 - Elsevier
In order to assess morphological and functional plasticity of the thyroid gland in aging the
effects of fasting and refeeding on the thyroid morphology and thyroid hormone serum levels
were compared with morphometry and RIA in young and old rats. Young (4 months) and old
(24 months) male Wistar rats were fasted for 40 h and sampled, or fasted and fed thereafter
for 4 or 24 h. In control (fed) old animals the thyroid follicules were larger, the follicular
epithelium was smaller and colloid resorption was smaller than in young rats.'Thyroid …