Subcutaneous graft of D1 mouse mesenchymal stem cells leads to the formation of a bone-like structure
O Juffroy, D Noël, A Delanoye, O Viltart, I Wolowczuk… - Differentiation, 2009 - Elsevier
Mesenchymal stem cells (MSC) are capable of both self-renewal and multi-lineage
differentiation into mesoderm-type cells such as osteoblasts, chondrocytes, adipocytes and
myocytes. Together the multipotent nature of MSCs and the facility to expand them in vitro
make these cells ideal resources for regenerative medicine, particularly for bone
reconstruction, and therefore research efforts focused on defining efficient protocols for
directing their differentiation into the requisite lineage. Despite much progress in identifying …
differentiation into mesoderm-type cells such as osteoblasts, chondrocytes, adipocytes and
myocytes. Together the multipotent nature of MSCs and the facility to expand them in vitro
make these cells ideal resources for regenerative medicine, particularly for bone
reconstruction, and therefore research efforts focused on defining efficient protocols for
directing their differentiation into the requisite lineage. Despite much progress in identifying …