The complex dialogue between (myo) fibroblasts and the extracellular matrix during skin repair processes and ageing

N Vedrenne, B Coulomb, A Danigo, F Bonté… - Pathologie …, 2012 - Elsevier
The fibroblasts and the myofibroblasts are key players for maintaining skin homeostasis and
for orchestrating physiological tissue repair. The (myo) fibroblasts are embedded in a
sophisticated extracellular matrix (ECM) that they secrete, and a complex and interactive
dialogue exists between (myo) fibroblasts and their microenvironment. The composition of
the ECM around (myo) fibroblasts is variable depending on the situation and, in addition to
the secretion of the ECM, the (myo) fibroblasts, by secreting matrix metalloproteinases and …