Trophoblast fusion: fusogenic proteins, syncytins and ADAMs, and other prerequisites for syncytial fusion
B Huppertz, C Bartz, M Kokozidou - Micron, 2006 - Elsevier
Trophoblast fusion in the placenta is an event of major importance for the preservation of a
healthy pregnancy. This process takes place throughout pregnancy and is crucial for the
maintenance of the syncytiotrophoblast layer, the direct border between maternal blood and
fetal tissues. Different regulatory proteins have been reported that are involved in
trophoblast fusion. Syncytin-1 is a candidate regulator of fusion together with its receptors
ASCT2 (RDR) and ASCT1. Little is known about the receptor properties and the interactions …
healthy pregnancy. This process takes place throughout pregnancy and is crucial for the
maintenance of the syncytiotrophoblast layer, the direct border between maternal blood and
fetal tissues. Different regulatory proteins have been reported that are involved in
trophoblast fusion. Syncytin-1 is a candidate regulator of fusion together with its receptors
ASCT2 (RDR) and ASCT1. Little is known about the receptor properties and the interactions …