Bacterial interference for prevention of urinary tract infection: a prospective, randomized, placebo-controlled, double-blind pilot trial

RO Darouiche, JI Thornby, CC Stewart… - Clinical infectious …, 2005 - academic.oup.com
RO Darouiche, JI Thornby, CC Stewart, WH Donovan, RA Hull
Clinical infectious diseases, 2005academic.oup.com
This prospective, randomized, placebo-controlled, double-blind pilot trial examined the
efficacy of bacterial interference in preventing urinary tract infection (UTI) in 27 patients with
spinal cord injury. Patients whose bladders became colonized with Escherichia coli 83972
were half as likely (P=. 01) than noncolonized patients to develop UTI during the subsequent
year.
Abstract
This prospective, randomized, placebo-controlled, double-blind pilot trial examined the efficacy of bacterial interference in preventing urinary tract infection (UTI) in 27 patients with spinal cord injury. Patients whose bladders became colonized with Escherichia coli 83972 were half as likely (P = .01) than noncolonized patients to develop UTI during the subsequent year.
Oxford University Press