Oral probiotics prevent necrotizing enterocolitis in very low birth weight preterm infants: a multicenter, randomized, controlled trial

HC Lin, CH Hsu, HL Chen, MY Chung, JF Hsu… - …, 2008 - publications.aap.org
OBJECTIVE. The goal was to investigate the efficacy of orally administered probiotics in
preventing necrotizing enterocolitis for very low birth weight preterm infants. METHODS. A
prospective, blinded, randomized, multicenter controlled trial was conducted at 7 NICUs in
Taiwan, to evaluate the beneficial effects of probiotics in necrotizing enterocolitis among
very low birth weight infants (birth weight:< 1500 g). Very low birth weight infants who
survived to start enteral feeding were eligible and were assigned randomly to 2 groups after …