mTOR is an evolutionarily conserved serine/threonine kinase that plays a central role in
integrating environmental cues in the form of growth factors, amino acids, and energy. In the
study of the immune system, mTOR is emerging as a critical regulator of immune function
because of its role in sensing and integrating cues from the immune microenvironment. With
the greater appreciation of cellular metabolism as an important regulator of immune cell
function, mTOR is proving to be a vital link between immune function and metabolism. In this …