[HTML][HTML] IκB–NF-κB structures: at the interface of inflammation control
PA Baeuerle - Cell, 1998 - cell.com
Cell, 1998•cell.com
The dramatic difference between healthy and acutely or chronically inflamed tissue is due to
the new expression of a host of proteins not normally needed by the organism. Many of the
genes encoding such proteins are turned on by NF-κB, a transcription factor that is in an
inactive form in the cytoplasm and is swiftly activated by a large variety of proinflammatory
and noxious stimuli (reviewed in
the new expression of a host of proteins not normally needed by the organism. Many of the
genes encoding such proteins are turned on by NF-κB, a transcription factor that is in an
inactive form in the cytoplasm and is swiftly activated by a large variety of proinflammatory
and noxious stimuli (reviewed in
The dramatic difference between healthy and acutely or chronically inflamed tissue is due to the new expression of a host of proteins not normally needed by the organism. Many of the genes encoding such proteins are turned on by NF-κB, a transcription factor that is in an inactive form in the cytoplasm and is swiftly activated by a large variety of proinflammatory and noxious stimuli (reviewed in
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