Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting
SR Steinhubl, WA Tan, JM Foody, EJ Topol… - Jama, 1999 - jamanetwork.com
ContextThrombotic thrombocytopenic purpura (TTP) is a rare and often fatal disorder
characterized by thrombocytopenia, microangiopathic hemolytic anemia, mental status
changes, and renal dysfunction. Ticlopidine hydrochloride is 1 of several drugs that have
been associated with this disorder and is currently used routinely in the approximately
500,000 patients per year in the United States who undergo a percutaneous coronary
intervention involving a stent. ObjectivesTo determine the incidence and describe the …
characterized by thrombocytopenia, microangiopathic hemolytic anemia, mental status
changes, and renal dysfunction. Ticlopidine hydrochloride is 1 of several drugs that have
been associated with this disorder and is currently used routinely in the approximately
500,000 patients per year in the United States who undergo a percutaneous coronary
intervention involving a stent. ObjectivesTo determine the incidence and describe the …