[HTML][HTML] Brief report: natural history of individuals with clinically recognized monoclonal B-cell lymphocytosis compared with patients with Rai 0 chronic lymphocytic …
TD Shanafelt, NE Kay, KG Rabe, TG Call… - Journal of Clinical …, 2009 - ncbi.nlm.nih.gov
Journal of Clinical Oncology, 2009•ncbi.nlm.nih.gov
Purpose The diagnosis of monoclonal B-cell lymphocytosis (MBL) is used to characterize
patients with a circulating population of clonal B cells, a total B-cell count of less than 5× 10
9/L, and no other features of a B-cell lymphoproliferative disorder including
lymphadenopathy/organomegaly. The natural history of clinically identified MBL is unclear.
The goal of this study was to explore the outcome of patients with MBL relative to that of
individuals with Rai stage 0 chronic lymphocytic leukemia (CLL).
patients with a circulating population of clonal B cells, a total B-cell count of less than 5× 10
9/L, and no other features of a B-cell lymphoproliferative disorder including
lymphadenopathy/organomegaly. The natural history of clinically identified MBL is unclear.
The goal of this study was to explore the outcome of patients with MBL relative to that of
individuals with Rai stage 0 chronic lymphocytic leukemia (CLL).
Abstract
Purpose
The diagnosis of monoclonal B-cell lymphocytosis (MBL) is used to characterize patients with a circulating population of clonal B cells, a total B-cell count of less than 5× 10 9/L, and no other features of a B-cell lymphoproliferative disorder including lymphadenopathy/organomegaly. The natural history of clinically identified MBL is unclear. The goal of this study was to explore the outcome of patients with MBL relative to that of individuals with Rai stage 0 chronic lymphocytic leukemia (CLL).
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