Estrogen carcinogenesis in breast cancer
JD Yager, NE Davidson - New England Journal of Medicine, 2006 - Mass Medical Soc
New England Journal of Medicine, 2006•Mass Medical Soc
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Estrogen exposure is a major determinant of the risk of breast cancer. This article reviews how genotoxic, mutagenic metabolites of estrogen and stimulation of tissue growth by the hormone participate in the pathogenesis of breast cancer.
The New England Journal Of Medicine