[HTML][HTML] Kindlin-1 is a phosphoprotein involved in regulation of polarity, proliferation, and motility of epidermal keratinocytes

C Herz, M Aumailley, C Schulte… - Journal of biological …, 2006 - ASBMB
A novel family of focal adhesion proteins, the kindlins, is involved in attachment of the actin
cytoskeleton to the plasma membrane and in integrin-mediated cellular processes.
Deficiency of kindlin-1, as a result of loss-of-function mutations in the KIND1 gene, causes
Kindler syndrome, an autosomal recessive genodermatosis characterized by skin blistering,
progressive skin atrophy, photosensitivity and, occasionally, carcinogenesis. Here we
characterized authentic and recombinantly expressed kindlin-1 and show that it is localized …